FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224] - Formalin-fixed, paraffin-embedded human Cerebellum stained with FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).

Immunohistochemistry-Paraffin: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224] - Formalin-fixed, paraffin-embedded human Testicular Cancer stained with FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).

Protein Array: FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free [NBP3-08224] - Analysis of Protein Array containing >19,000 full-length human proteins using FCRN/FCGRT Mouse Monoclonal Antibody (FCRN/FCGRT/2932).

• Reactivity: Hu
• Applications: IHC, MA
• Clone: FCGRT/2932
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1 mg/ml

FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free Summary

• Description: 1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07228).
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.
• Immunogen: Recombinant fragment of human FCRN/FCGRT protein (around aa 24-215) (Exact sequence is proprietary) (Uniprot: P55899)
• Localization: Cell Surface and Cytoplasmic
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCGRT
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 2-4 ug/ml
  • Protein Array
• Application Notes: Immunohistochemistry Formalin-fixed: 2-4ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
• Theoretical MW: 46 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: 10 mM PBS
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for FCRN/FCGRT Antibody (FCGRT/2932) - Azide and BSA Free

• alpha-chain
• Fc fragment of IgG, receptor, transporter, alpha
• FCGRT
• FcRn alpha chain
• FCRN
• FCRNimmunoglobulin receptor, intestinal, heavy chain
• IgG Fc fragment receptor transporter alpha chain
• IgG receptor FcRn large subunit p51
• major histocompatibility complex class I-like Fc receptor
• Neonatal Fc receptor
• neonatal Fc-receptor for Ig

Background

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCGRT