FCRL2/FcRH2 Antibody (296902) [Janelia Fluor® 669]

• Reactivity: Hu
• Applications: WB, Flow, CyTOF-ready
• Clone: 296902
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

FCRL2/FcRH2 Antibody (296902) [Janelia Fluor® 669] Summary

• Additional Information: Clone 296902 was used by HLDA to establish CD designation
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human FCRL2/FcRH2
  Glu15-Asp395
  Accession # Q96LA5
• Specificity: Detects human FCRL2/FcRH2 and FCRL5/FcRH5 in Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human FCRL1, FCRL3, and FCRL4 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCRL2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for FCRL2/FcRH2 Antibody (296902) [Janelia Fluor® 669]

• CD307b antigen
• CD307b
• Fc receptor homolog 2
• Fc receptor-like 2
• FcRH2
• FCRH2SPAP1B
• FCRL2
• FcR-like protein 2
• IFGP family protein 4
• IFGP4
• Immunoglobulin receptor translocation-associated protein 4
• immunoglobulin superfamily Fc receptor, gp42
• IRTA4
• IRTA4SPAP1C
• SH2 domain containing phosphatase anchor protein 1
• SH2 domain-containing phosphatase anchor protein 1Fc receptor-like protein 2
• SPAP1
• SPAP1A
• SPAP1immune receptor translocation-associated protein 4

Background

The FCRL2 gene codes for a member of the immunoglobulin receptor superfamily, a Fc receptor-like protein 2 that has five isoforms: isoform 1: 508 amino acids long, 55 kDA; isoform 2: 255 amino acids long, 27 kDA; isoform 3: 192 amino acids long, 20 kDA; isoform 4L 144 amino acids long, 15 kDA; and isoform 5: 202 amino acids long, 22 kDA. This protein is clustered on the long arm of chromosome 1 and may play a regulatory role in normal as well as neoplastic B cell development. FCRL2 is linked to leukemia, tonsillitis, hepatitis, and HIV type 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRL2