Human Fc gamma RIIB/CD32b ELISA Kit Summary
Sensitivity |
85 pg/mL |
Inter-Assay |
CV% < 12% |
Intra-Assay |
CV% < 10% |
Spike Recovery |
100.33% |
Sample Volume |
100 uL |
Kit Type |
ELISA Kit |
Gene |
FCGR2B |
Applications/Dilutions
Dilutions |
|
Application Notes |
FCGR2B (Human) ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of human FCGR2B. |
Reactivity Notes
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for Human Fc gamma RIIB/CD32b ELISA Kit
Background
Low affinity IgG Fc receptor gamma II (Fc-gamma II), also known as CD32, is a member of the immunoreceptor tyrosine-based activating/inhibitory motif (ITAM/ITIM) family. Fc gamma receptors play a critical role in immunity by linking the IgG antibody mediated response with the regulatory functions of the immune system (1). Three classes of Fc gamma receptor exist; Fc gamma RI (CD64, a high affinity receptor), Fc gamma RII, and RIII (CD32 and CD16 respectively, both low affinity receptors). Fc gamma RIIa is an activating receptor, while RIIb1, RIIb2, and RIIb3 are inhibitory receptors generated by alternative splicing (1-2). Fc gamma RIIa is critical for antigen-presenting-cell activation and Fc gamma RIIb downregulates B-cell functions (3). Fc gamma RIIb has also been known to block the inflammatory immune response in mice (4). Once phosphorylated on tyrosine residues, Fc gamma RIIb associates with SHIP to downregulate phagocytosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are
guaranteed for 6 months from date of receipt.
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Product General Protocols
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FAQs for Fc gamma RIIB/CD32b ELISA Kit (KA2177). (Showing 1 - 1 of 1 FAQ).
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wondering what the difference is between your quantikine and duo set elisas?
- Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.
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