FANCC Antibody (8F3) [Biotin]

Product Discontinued

FANCC Antibody (8F3) [Biotin] Summary

• Immunogen: A synthetic peptide made to a region of the C-terminus of human FANCC (within residues 450-558) [Swiss-Prot# Q00597].
• Localization: Nucleus. Cytoplasm. Note= The major form is nuclear. The minor form is cytoplasmic.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: FANCC
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation
  • Western Blot
• Application Notes: This FANCC antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot where a band is seen ~63 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Theoretical MW: 63 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Reactivity Notes

Human

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for FANCC Antibody (8F3) [Biotin]

• FA Complementation Group C
• FA3
• FACC
• FACCProtein FACC
• FACFanconi anemia group C protein
• FANCC
• Fanconi anemia, complementation group C
• FLJ14675

Background

Fanconi anemia group C protein is a DNA repair protein. It may function as a cell cycle checkpoint or in postreplication repair. FANCC may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in this portein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in many congenital malformations and predisposition to malignant formations.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FANCC