FANCC Antibody (24GB8340)

• Reactivity: Hu
• Applications: WB, Mycoplasma
• Clone: 24GB8340
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

FANCC Antibody (24GB8340) Summary

• Immunogen: Recombinant protein of human FANCC (Uniprot: Q00597)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: FANCC
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for FANCC Antibody (24GB8340)

• FA Complementation Group C
• FA3
• FACC
• FACCProtein FACC
• FACFanconi anemia group C protein
• FANCC
• Fanconi anemia, complementation group C
• FLJ14675

Background

The Fanconi anemia group C protein (FANCC) is a member of the Fanconi anemia complementation. FANCC functions as a cell cycle checkpoint to delay the onset of apoptosis and promotes homologous recombination repair of damaged DNA. FANCC may be important for the maintenance of chromosome stability and reparation of interstrand DNA cross linkages. Defects in FANCC portein result in a disease state, Fanconi anemia, an autosomal recessive disorder. Fanconi anemia results in many congenital malformations and predisposition to malignant formations.

FANCC antibodies are useful for DNA repair studies and cell cycle research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FANCC