FAM3D Antibody

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

FAM3D Antibody Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human FAM3D
  Trp39-Phe224
  Accession # Q96BQ1
• Specificity: Detects human FAM3D in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse FAM3D is observed and 5% cross-reactivity with recombinant human (rh) FAM3A, rhFAM3B, and rhFAM3C is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FAM3D
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FAM3D Antibody

• cytokine-like protein EF-7
• EF7
• FAM3D
• family with sequence similarity 3, member D
• OIT1

Background

FAM3D, also known as EF-7, belongs to the novel cytokine-like family whose members are secreted four-helix bundle proteins. Human FAM3D is abundantly expressed in placenta as a 224 amino acid (aa) residue precursor with a 25 aa signal sequence. The aa sequence of mature human FAM3D is 74% identical to that of mouse FAM3D.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FAM3D Antibody (AF2869)(1)

Publication using AF2869

• W Liang, X Peng, Q Li, P Wang, P Lv, Q Song, S She, S Huang, K Chen, W Gong, W Yuan, V Thovarai, T Yoshimura, C O'huigin, G Trinchieri, J Huang, S Lin, X Yao, X Bian, W Kong, J Xi, JM Wang, Y Wang FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis Nat Commun, 2020-11-20;11(1):5912. 11/20/2020 [PMID: 33219235]

Bioinformatics

• Gene Symbol: FAM3D
• Uniprot:
  • Q96BQ1()