Factor XIIIa Antibody

Immunohistochemistry-Paraffin: Factor XIIIa Antibody [NB600-1202] - Formalin fixed paraffin embedded human placenta stained with Factor XIIIa antibody (NB600-1202).

Product Discontinued

Factor XIIIa Antibody Summary

• Immunogen: Recombinant protein corresponding to subunit-A of coagulation Factor XIIIa.
• Localization: Cytoplasmic, nuclear
• Marker: Dendritic Cell Marker
• Specificity: This reacts with the 160 kDa (unreacted dimer) and 80 kDa (reduced monomer) protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: F13A1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilutions / concentrations should be determined by the end user.For formalin fixed paraffin embedded sections, perform heat mediated antigen retrieval using 10mM citrate buffer pH 6.0 before commencing with the IHC staining protocol.

Reactivity Notes

Cross-reacts with Human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.4) and 0.2% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for Factor XIIIa Antibody

• bA525O21.1 (coagulation factor XIII, A1 polypeptide)
• coagulation factor XIII A chain
• coagulation factor XIII, A1 polypeptide
• Coagulation factor XIIIa
• EC 2.3.2.13
• F13A
• F13A1
• F13Acoagulation factor XIII, A polypeptide
• factor XIIIa
• fibrin stabilizing factor, A subunit
• fibrinoligase
• FSF, A Subunit
• Protein-glutamine gamma-glutamyltransferase A chain
• TGase
• Transglutaminase A chain
• transglutaminase. plasma

Background

Factor XIII is a beta-globulin found in plasma and is composed of two subunits. It is the catalytic subunit and is a dimer of M.W. 160 kDa. Factor XIII is a dermal dendrocyte marker and shows variable reaction with these types of tumors. Factor XIII can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: F13A1
• Entrez:
  • 2162(Human)