Factor XIIIa Products

Factor XIIIa Antibody
Factor XIIIa Antibody
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Factor XIIIa Antibody Pair
Factor XIIIa Antibody Pair
Species: Hu
Applications: WB, IP
Factor XIIIa Overexpression L ...
Factor XIIIa Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human F13A1 His-t ...
Recombinant Human F13A1 His-tag Pr...
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
Recombinant Human Factor XIII ...
Recombinant Human Factor XIIIa Pro...
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Factor XIIIa Recombinant Prot ...
Factor XIIIa Recombinant Protein A...
Species: Hu
Applications: AC


Factor XIII is a beta globulin found in plasma and is composed of two subunits. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Factor XIII A is the catalytic subunit and is a dimmer of molecular weight 160kDa. The B subunits do not have enzymatic activity and may serve as a plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon activation by the cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIII A, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. Factor XIII A is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system.


Entrez Human
Uniprot Human
Product By Gene ID 2162
Alternate Names
  • bA525O21.1 (coagulation factor XIII, A1 polypeptide)
  • transglutaminase. plasma
  • TGase
  • FSF, A subunit
  • EC
  • fibrinoligase
  • Transglutaminase A chain
  • fibrin stabilizing factor, A subunit
  • Protein-glutamine gamma-glutamyltransferase A chain
  • factor XIIIa
  • Coagulation factor XIIIa
  • F13Acoagulation factor XIII, A polypeptide
  • coagulation factor XIII A chain
  • coagulation factor XIII, A1 polypeptide

Research Areas for Factor XIIIa

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Cell Biology

PTMs for Factor XIIIa

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Bioinformatics Tool for Factor XIIIa

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