FABP7/B-FABP Antibody (2D2)

• Reactivity: Hu
• Applications: ELISA, Flow
• Clone: 2D2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.1 mg/ml

FABP7/B-FABP Antibody (2D2) Summary

• Immunogen: Peptide derived from human B-FABP sequence
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: FABP7
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunoassay
• Application Notes: For Flow Cytometry, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For functional studies, in vitro dilutions have to be optimized in user's experimental setting.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 0.2 um filtered solution in PBS, 0.1% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.1 mg/ml
• Purity: Protein G purified

Alternate Names for FABP7/B-FABP Antibody (2D2)

• BFABP
• B-FABP
• B-FABPDKFZp547J2313
• BLBP
• BLBPMRG
• Brain lipid-binding protein
• Brain-type fatty acid-binding protein
• FABP7
• FABPBbrain lipid binding protein
• fatty acid binding protein 7, brain
• Fatty acid-binding protein 7
• fatty acid-binding protein, brain
• Mammary-derived growth inhibitor related
• mammary-derived growth inhibitor-related

Background

The monoclonal antibody clone-2D2 recognizes human brain fatty acid binding protein (B-FABP, FABP7) of both natural and recombinant origin. The B-FABP protein is derived from the human FABP7 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. B-FABP is localized in the brain and other neural tissues.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FABP7