FABP6 Antibody (201) [CoraFluor™ 1]

CoraFluor™ 1, amine reactive (Catalog:7920) and CoraFluor™ 2, amine reactive (Catalog # 7950) are terbium-based probes that have been developed for use as TR-FRET donors. They emit wavelengths compatible with commonly used fluorescent acceptor dyes such as BODIPY® (or BDY) and Janelia Fluor® dyes, FITC (Catalog # 5440), TMR and Cyanine 5 (Catalog # 5436). CoraFluor™ fluorescence is brighter and more stable in biological media than existing TR-FRET donors, leading to enhanced sensitivity and improved data generation. CoraFluor™ 1 exhibits excitation upon exposure to a 337 nm UV laser.

• Reactivity: Hu
• Applications: Flow, ICC/IF
• Clone: 201
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: CoraFluor 1

FABP6 Antibody (201) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human FABP6 (Accession#: AAH22489.1; Met1-Ala128).
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: FABP6
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for FABP6 Antibody (201) [CoraFluor™ 1]

• FABP6
• fatty acid binding protein 6, ileal
• Fatty acid-binding protein 6
• Gastrotropin
• I-15P
• I-15PIntestinal 15 kDa protein
• IBABP
• I-BABPIntestinal bile acid-binding protein
• I-BALB
• I-BAP
• ILBP
• ILBP3
• ILBPGT
• ileal bile acid binding protein
• ILLBP
• ILLBPIleal lipid-binding protein
• illeal lipid-binding protein

Background

Belonging to the Fatty-acid binding protein (FABP) family of cytoplasmic proteins, FABP6 binds long-chain fatty acids and other hydrophobic ligands. This protein encodes the ileal fatty acid binding protein and binds to bile salts and bilirubins. This protein is also known to stimulate gastric acid and pepsinogen secretion. The main functions of FABP6 include fatty acid uptake, transport, and metabolism. It's also involved in bile acid and bile salt transport, bile acid metabolic process, lipid metabolic process, negative regulation of cell proliferation, small molecule metabolic process and steroid metabolic process transport. Popular diseases for FABP6 include colorectal cancer, major depression and colorectal adenocarcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FABP6