Exostosin-like 3/EXTL3 Antibody (311007) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 311007
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Exostosin-like 3/EXTL3 Antibody (311007) [Alexa Fluor® 405] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3
  Thr52-Ile919
  Accession # O43909
• Specificity: Detects human Exostosin-like 3/EXTL3 in direct ELISAs and Western blots.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Exostosin-like 3/EXTL3 Antibody (311007) [Alexa Fluor® 405]

• botv
• DKFZp686C2342
• EC 2.4.1.223
• exostoses (multiple)-like 3
• Exostosin like 3
• Exostosin-like 3
• EXTL1L
• EXTL3
• EXTR1BOTV
• EXT-related protein 1
• Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
• Hereditary multiple exostoses gene isolog
• KIAA0519
• Multiple exostosis-like protein 3
• Putative tumor suppressor protein EXTL3
• reg receptor
• REG
• REGR
• RPR

Background

EXTL3 is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The amino acid sequence of rhEXTL3 is 98%, 97%, 88%, and 83% identical to that of dog, rat/mouse, Xenopus and zebrafish.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.