Exosome Component 9 Antibody [DyLight 650]

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Product Details

Summary
Reactivity Hu, Mu, Ch, BvSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 650

Exosome Component 9 Antibody [DyLight 650] Summary

Immunogen
A genomic peptide made to an internal region of human Exosome Component 9 (within residues 250-439). [Swiss-Prot Q06265]
Localization
Cytoplasm. Nucleus - nucleolus.
Predicted Species
Bovine (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
EXOSC9
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This EXOSC9 antibody is useful for IHC-P, ICC/IF and Western blot, where a band is seen ~75 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended. NBP1-71702 has also been successfully used for IP as reported by a customer review.

Reactivity Notes

Human, Mouse and Chicken. Immunogen has 83% identity to rat and 90% identity to bovine.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Exosome Component 9 Antibody [DyLight 650]

  • Autoantigen PM/Scl 1
  • EC 3.1.13
  • exosome component 9Polymyositis/scleroderma autoantigen 75 kDa
  • p6
  • PM/Scl-75P75 polymyositis-scleroderma overlap syndrome-associated autoantigen
  • PMSCL175kD
  • polymyositis/scleroderma autoantigen 1 (75kD)
  • Polymyositis/scleroderma autoantigen 1
  • polymyositis/scleroderma autoantigen 1, 75kDa

Background

Exosome component 9 is part of the 3' -> 5' exoribonuclease complex that helps to degrade unstable mRNA. It binds to ARE-containing RNAs and performs 3' end trimming and degradation. These activities lead toward the maturation of RNA into more stable forms, which then become involved in transcription and translation. In the related Arabidopsis equivalent, loss of function of this protein is a lethal mutation. In ruminants, EXOSC9 is differentially expressed throughout the gut at different stages of development. EXOSC9 seems to be important in the degradation of histone mRNA and may be important in some downstream epigenetic effects.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol EXOSC9