ETV6/Tel Antibody [PE]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: PE

ETV6/Tel Antibody [PE] Summary

• Immunogen: E. coli-derived recombinant human ETV6
  Ser2-Asp111
  Accession # P41212
• Specificity: Detects human ETV6 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: ETV6
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for ETV6/Tel Antibody [PE]

• ETS translocation variant 6
• ets variant 6
• ets variant gene 6 (TEL oncogene)
• ETS-related protein Tel1
• ETV6
• TEL
• TEL/ABL
• TEL1
• TELTEL1 oncogene
• transcription factor ETV6

Background

Tel encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N terminal pointed (PNT) domain that is involved in the protein protein interactions with itself and other proteins, and a C terminal DNA binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ETV6