ETV3 Antibody (1C11) - Azide and BSA Free

ELISA: ETV3 Antibody (1C11) [H00002117-M02-100ug] - Detection limit for recombinant GST tagged ETV3 is 10 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA
• Clone: 1C11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

ETV3 Antibody (1C11) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse ETV3 Antibody (1C11) - Azide and BSA Free (H00002117-M02-100ug) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: ETV3 (AAH22868, 1 a.a. ~ 143 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MKAGCSIVEKPEGGGGYQFPDWAYKTESSPGSRQIQLWHFILELLQKEEFRHVIAWQQGEYGEFVIKDPDEVARLWGRRKCKPQMNYDKLSRALRYYYNKRILHKTKGKRFTYKFNFNKLVMPNYPFINIRSSGKIQTLLVGN
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ETV3
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ETV3 Antibody (1C11) - Azide and BSA Free

• bA110J1.4
• ETS domain transcriptional repressor PE1
• ETS translocation variant 3
• ets variant 3
• ets variant gene 3, ETS family transcriptional repressor
• METS
• Mitogenic Ets transcriptional suppressor
• PE-1ets variant gene 3
• PE1FLJ79173

Background

The ETV3 gene encodes an ETS translocation variant 3 protein, that in isoform 1 is 512 amino acids long at 57 kDA and in isoform 2 is 143 amino acids long at nearly 17 kDA. This protein functions in terminal macrophage differentiation as a transcriptional repressor that contributes to growth arrest. It also represses MMP1 promoter activity and interacts with the MYC and DDX20 genes. ETV3 is linked to diseases heart disease, hypertension, ADHD, and conduct disorder.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ETV3
• Entrez:
  • 2117(Human)
• OMIM:
  • 164873(Human)
• Uniprot:
  • AAH22868(Human)