ETV3 Products

Description

The ETV3 gene encodes an ETS translocation variant 3 protein, that in isoform 1 is 512 amino acids long at 57 kDA and in isoform 2 is 143 amino acids long at nearly 17 kDA. This protein functions in terminal macrophage differentiation as a transcriptional repressor that contributes to growth arrest. It also represses MMP1 promoter activity and interacts with the MYC and DDX20 genes. ETV3 is linked to diseases heart disease, hypertension, ADHD, and conduct disorder.

Bioinformatics

Entrez	2117 Human
Uniprot	AAH22868 Human NM_005240 Human NP_005231 Human P41162 Human
Product By Gene ID	2117
Alternate Names	bA110J1.4 ETS domain transcriptional repressor PE1 ETS translocation variant 3 ets variant 3 ets variant gene 3, ETS family transcriptional repressor METS Mitogenic Ets transcriptional suppressor PE-1ets variant gene 3 PE1FLJ79173