ETV1 Antibody (815207) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Clone: 815207
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

ETV1 Antibody (815207) [Alexa Fluor™ Plus 647] Summary

• Specificity: Detects human ETV1 in direct ELISAs and Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ETV1 Antibody (815207) [Alexa Fluor™ Plus 647]

• DKFZp781L0674
• ER81
• ER81ets variant gene 1
• ETS translocation variant 1
• ets variant 1
• Ets-related protein 81
• ETV1
• MGC104699
• MGC120533
• MGC120534

Background

ETS translocation variant 1 is a protein that in humans is encoded by the ETV1 gene. ETV-1, ETV-4 and ETV-5 proteins form the PEA3 subfamily of ETS transcription factors. Posttranslational modifications in this subfamily promote cell proliferation, motility and invasion.  Disregulation of ETV-1 has been observed in gastrointestinal stromal and protatic tumors, and in triple-negative breast cancer. Human ETV-1 is a 477 aminoacids (aa) protein with at least six known isoforms. Over the immunogen used in this antibody (aa120-190), ETV-1 sequences are 96% identical to mouse and rat ETV-1 sequences.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.