ERLIN1 Antibody

Western Blot: ERLIN1 Antibody [NBP1-45206] - (0.5ug/ml) staining of Human Placenta lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

ERLIN1 Antibody Summary

• Description: Novus Biologicals Goat ERLIN1 Antibody (NBP1-45206) is a polyclonal antibody validated for use in WB and ELISA. Anti-ERLIN1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-EALEPSGENVIQNKE corresponding to C-Terminus according to NP_006450.2.
• Epitope: C-Terminus
• Specificity: Reported variants represent identical protein: NP_006450.2, NP_001094096.1
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ERLIN1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
  • Western Blot 0.3 - 1 ug/ml
• Application Notes: WB: Approx. 38 kDa band observed in human placenta lysates (calculated MW of 39.2 kDa band according to NP_006450.2).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ERLIN1 Antibody

• Band_7 23-211 Keo4 (Interim) similar to C.elegans protein C42C1.9
• C10orf69
• chromosome 10 open reading frame 69
• Endoplasmic reticulum lipid raft-associated protein 1
• ER lipid raft associated 1
• Erlin-1
• KE04SPFH domain-containing protein 1
• KEO4
• Protein KE04
• SPFH domain family, member 1
• SPFH1
• Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1

Background

ERLIN1 is a component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ERLIN1 Antibody (NBP1-45206)(1)

Publication using NBP1-45206

• Browman DT, Resek ME, Zajchowski LD, Robbins SM. Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER. J Cell Sci 2006-08-01 [PMID: 16835267]

Bioinformatics

• Gene Symbol: ERLIN1
• Entrez:
  • 10613(Human)
• Uniprot:
  • NP_006450.2(Human)