EPX Native Protein

SDS-Page: EPX Native Protein [NBP2-12563]

Product Discontinued

EPX Native Protein Summary

• Description: Native EPX
  
  

  Source:Human eosinophils
  Amino Acid Sequence:(P11678)

• Source: Human eosinophils
• Protein/Peptide Type: Native Protein
• Gene: EPX
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Application Notes: Specific activity: >180 units per mg protein after lyophilization
• Theoretical MW: 70.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from 20 mM NaH2PO4, pH 7.5, and 150 mM NaCI
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in deionized H2O. Aliquot and store at -20C. Avoid freeze-thaw cycles.

Alternate Names for EPX Native Protein

• EC 1.11.1.7
• eosinophil peroxidase
• EPOEPER
• EPPEC 1.11.1
• EPX-PEN

Background

Native, human eosinophil peroxidase is a secreted hemoprotein that catalyzes oxidations of various substrates by hydrogen peroxide. Together with other leukocyte-derived enzymes, such as Myeloperoxidase, EPO plays an important role in the pathogenesis of asthma by mediating oxidative events that lead to the production of ROS (reactive oxygen species) and RNS (reactive nitrogen species).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: EPX