DYRK3 Antibody (563518) [DyLight 405]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 563518
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 405

DYRK3 Antibody (563518) [DyLight 405] Summary

• Immunogen: E. coli-derived recombinant human DYRK3
  Asn52-Glu167
  Accession # O43781
• Specificity: Detects human, mouse, and rat DYRK3 in Western blots.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: DYRK3
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for DYRK3 Antibody (563518) [DyLight 405]

• dual specificity tyrosine-phosphorylation-regulated kinase 3
• dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
• dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 5
• DYRK3
• DYRK5
• EC 2.7.12
• EC 2.7.12.1
• hYAK3-2
• protein kinase Dyrk3
• REDK
• REDKRED
• Regulatory erythroid kinase
• YAK3-2

Background

DYRK3, or dual specificity tyrosine-phosphorylation-regulated kinase 3, is a negative regulator of EPO-dependent erythropoiesis and may place an upper limit on red cell production during stress erythropoiesis. DYRK3 inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells, and may also act by regulating CREB/CRE signaling.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DYRK3