Dynamin 3 Antibody (SR2308) - BSA Free

Western Blot: Dynamin 3 Antibody (SR2308) [NBP3-22364] - Western blot analysis using NBP3-22364 in Human fetal brain lysate.

• Reactivity: Hu, Mu
• Applications: WB
• Clone: SR2308
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Dynamin 3 Antibody (SR2308) - BSA Free Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human Dynamin 3 (Uniprot #: Q9UQ16)
• Specificity: Detects endogenous levels of total Dynamin 3
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DNM3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:2000
• Theoretical MW: 97 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for Dynamin 3 Antibody (SR2308) - BSA Free

• Dyna III
• dynamin 3
• dynamin family member
• dynamin-3
• EC 3.6.5.5
• MGC70433
• T-dynamin
• testicular

Background

The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin 1 is expressed exclusively in neurons, Dynamin 2 is ubiquitously expressed, and Dynamin 3 is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DNM3