DSPG3/EPYC Antibody [Biotin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

DSPG3/EPYC Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human DSPG3
  Ala20-Val322
  Accession # Q99645
• Specificity: Detects human DSPG3 in Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse DSPG3 is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: EPYC
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DSPG3/EPYC Antibody [Biotin]

• Dermatan sulfate proteoglycan 3dermatan sulphate proteoglycan 3
• DSPG3
• DSPG3proteoglycan-lb
• Epiphycan
• EPYC
• PGLB
• PG-Lb
• Proteoglycan-Lb
• SLRR3B
• SLRR3Bepiphycan proteoglycan
• Small chondroitin/dermatan sulfate proteoglycan

Background

DSPG3, also known as proteoglycan-Lb and Epiphycan, is a 95 - 100 kDa member of the class III subfamily within the SLRP (small leucine-rich proteoglycan) family. The secreted 303 aa mature segment contains multiple sites for O-linked glycanation, and seven leucine-rich repeats, flanked by N- and C-terminal cysteine-rich regions. Human DSPG3 shares 96%, 95%, 85% and 84% aa sequence identity with canine, bovine, rat and mouse DSPG3, respectively. DSPG3 is principally a component of cartilage.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EPYC
• Uniprot:
  • Q99645()