DSCAM-L1 Antibody [Unconjugated]

Images

 
A172 human glioblastoma cell line was stained with Goat Anti-Human DSCAM‑L1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3315, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

DSCAM-L1 Antibody [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human DSCAM-L1
Glu19-Lys1591
Accession # Q8TD84
Specificity
Detects human DSCAM-L1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human DSCAM is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
DSCAML1
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.1 ug/mL
  • Flow Cytometry 2.5 ug/10^6 cells
  • CyTOF-ready
Publications
Read Publication using
AF3315 in the following applications:

  • ICC
    1 publication

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DSCAM-L1 Antibody [Unconjugated]

  • Down syndrome cell adhesion molecule like 1
  • Down syndrome cell adhesion molecule-like protein 1
  • Downs syndrome cell adhesion molecule like 1
  • DSCAM2
  • DSCAML1
  • DSCAM-L1
  • KIAA1132Down syndrome cell adhesion molecule 2

Background

DSCAM-L1 is a 250 kDa type I transmembrane Ig superfamily glycoprotein that is predominantly expressed in Purkinje cells and neurons of the cerebral cortex and olfactory bulb.DSCAM-L1 mediates cell adhesion by cation-independent homophilic interactions. It may function in the formation and maintenance of neural networks and play a role in neural disorders such as Gilles de la Tourette and Jacobsen syndromes. Human DSCAM-L1 contains ten Ig-like C2-type domains and six fibronectin type-III domains. An alternately spliced isoform is generated by deletion of 211 amino acids near the N-terminal. Within the extracellular domain, human DSCAM-L1 shares 98% amino acid sequence identity with mouse and rat DSCAM-L1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for DSCAM-L1 Antibody (AF3315)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: ICC.


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(1)
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Bioinformatics

Gene Symbol DSCAML1
Uniprot