DSCAM Antibody [PE]

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: PE

DSCAM Antibody [PE] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human DSCAM long isoform
  Glu18-Met1595
  Accession # O60469
• Specificity: Detects human DSCAM in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human DSCAM-L1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: DSCAM
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for DSCAM Antibody [PE]

• CHD2-42
• CHD2-52
• Down syndrome cell adhesion molecule
• DSCAM
• human CHD2-52 down syndrome cell adhesion molecule, 10CHD2

Background

The Dscam gene encodes a large family of axon guidance receptors and immune receptors via alternative splicing, generating over 38000 isoforms. The gene has been shown to be required for axon guidance, specifically targeting individual neurons to their targets. The gene has also been shown to be involved in the immune system of the fly; different isoforms interact with different pathogens to elicit an immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DSCAM