Dopamine D5R/DRD5 Antibody - Pre-diluted

Product Discontinued

Dopamine D5R/DRD5 Antibody - Pre-diluted Summary

• Immunogen: Synthetic peptide corresponding to aa 459-477 of human D5DR.
• Specificity: This product is specific for D5DR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DRD5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin Neat
• Application Notes: IHC-P: ready-to-use for 10 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Reactivity Notes

Predicted by homology: Chicken, Canine, Porcine, Rabbit.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Prediluted antibody
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for Dopamine D5R/DRD5 Antibody - Pre-diluted

• D(1B) dopamine receptor
• D(5) dopamine receptor
• D1beta dopamine receptor
• DBDR
• Dopamine D5 R
• Dopamine D5 receptor
• Dopamine D5R
• dopamine receptor D1B
• dopamine receptor D5
• DRD1B
• DRD1BDBDR
• DRD1L2
• DRD1L2MGC10601
• DRD5

Background

The members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin, and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. Beta-adrenergic receptor bound to adrenaline activates adenylyl cyclase, while alpha 2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes; D1 and D2, which differ in their functional characteristics. D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DRD5
• Entrez:
  • 1816(Human)