DNA Primase small subunit Antibody [HRP]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: HRP

DNA Primase small subunit Antibody [HRP] Summary

• Immunogen: primase, DNA, polypeptide 1(49kDa). (Uniprot# P49642)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRIM1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for DNA Primase small subunit Antibody [HRP]

• DNA primase 1
• DNA primase 49 kDa subunit
• DNA primase small subunit
• DNA primase subunit 48
• EC 2.7.7
• EC 2.7.7.-
• MGC12308
• p49
• primase p49 subunit
• primase polypeptide 1, 49kDa
• primase, DNA, polypeptide 1 (49kDa)

Background

DNA Primase small subunit, also known by its gene name PRIM1, is a heterodimer that is composed of a small and large subunit. PRIM1 is 420 amino acids long and approximately 49kDa. The DNA Primase small subunit synthesizes RNA primers for the Okazaki fragments created during discontinuous DNA replication. Current research surrounding PRIM1 has shown a possible link with carcinomas, malaria, neuronitis, and osteosarcoma. DNA Primase small subunit has also been shown to interact with Histone cluster 1 H4/A, H4/B, H4/C, H4/D and H4/E in pathways such as DNA replication, DNA strand elongation, polymerase switching, and lagging strand synthesis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRIM1