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Dkk-1 Antibody

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Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB100-1450
    • Availability
      Product Discontinued

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Dkk-1 Antibody Summary

Immunogen
Peptide with sequence CDHHQASNSSRLHT corresponding to C-Terminus according to NP_036374.1.
Localization
Secreted
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
DKK1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1-3 ug/ml
Application Notes
WB: Approx. 38 kDa band observed in human spleen lysates is reported in scientific literature (PMID: 10383463).
Control
Dkk-1 Overexpression Lysate
Publications
Read Publication using NB100-1450.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Rat, Canine, Porcine, Bovine.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris (pH 7.3), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Dkk-1 Antibody

  • dickkopf (Xenopus laevis) homolog 1
  • dickkopf homolog 1 (Xenopus laevis)
  • dickkopf related protein-1
  • Dickkopf-1
  • dickkopf-related protein 1
  • Dkk1
  • Dkk-1
  • hDkk-1
  • SKdickkopf-1 like

Background

DKK1 is a secreted factor that has been linked to the function of osteoblasts. Elevated DKK1 levels in bone marrow plasma and peripheral blood from patients with multiple myeloma correlated with the gene-expression patterns of DKK1 and were associated with the presence of focal bone lesions. The production of DKK1, an inhibitor of osteoblast differentiation, by myeloma cells is associated with the presence of lytic bone lesions in patients with multiple myeloma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Dkk-1 Antibody
NB100-1450
Dkk-1 Antibody
Species: Hu
Applications: WB, ELISA, IHC

Publications for Dkk-1 Antibody (NB100-1450)(1)


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Product General Protocols

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Video Protocols

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Control Lysate(s)

Dkk-1 Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

Additional Dkk-1 Products

Research Areas for Dkk-1 Antibody (NB100-1450)

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Blogs on Dkk-1.

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Bioinformatics

Gene Symbol DKK1
Entrez
Uniprot