Dkk-1 Antibody (4D4)

Images

 
Western Blot: Dkk-1 Antibody (4D4) [H00022943-M01] - DKK1 monoclonal antibody (M01), clone 4D4 Analysis of DKK1 expression in HepG2.
Western Blot: Dkk-1 Antibody (4D4) [H00022943-M01] - DKK1 monoclonal antibody (M01), clone 4D4. Analysis of DKK1 expression in Jurkat.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4D4
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Dkk-1 Antibody (4D4) Summary

Immunogen
DKK1 (NP_036374, 81 a.a. ~ 181 a.a) partial recombinant protein with GST tag.QPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH
Specificity
DKK1 - dickkopf homolog 1 (Xenopus laevis)
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DKK1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500
  • ELISA
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Dkk-1 Antibody (4D4)

  • dickkopf (Xenopus laevis) homolog 1
  • dickkopf homolog 1 (Xenopus laevis)
  • dickkopf related protein-1
  • Dickkopf-1
  • dickkopf-related protein 1
  • Dkk1
  • Dkk-1
  • hDkk-1
  • SKdickkopf-1 like

Background

This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DKK1
Entrez
OMIM
Uniprot