DIP13B Antibody - BSA Free

Western Blot: DIP13B Antibody [NBP2-16165] - Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7. 5% SDS PAGE gel, diluted at 1:1000.

• Reactivity: Hu, Po, Bv
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

DIP13B Antibody - BSA Free Summary

• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human DIP13B. The exact sequence is proprietary.
• Localization: Early endosome membrane; Nucleus
• Predicted Species: Porcine (97%), Bovine (95%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: APPL2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500-1:3000
• Theoretical MW: 74 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 29705396). Rat reactivity reported in scientific literature (PMID: 30189216). Xenopus laevis (87%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for DIP13B Antibody - BSA Free

• Adapter protein containing PH domain, PTB domain and leucine zipper motif 2
• adaptor protein containing PH domain, PTB domain and leucine zipper motif 2
• adaptor protein, phosphotyrosine interaction, PH domain and leucine zippercontaining 2
• DCC-interacting protein 13-beta
• DIP13BDIP13 beta
• Dip13-beta
• FLJ10659dip13-beta

Background

Required for the regulation of cell proliferation in response to extracellular signals mediated by an early endosomal compartment. Links Rab5 to nuclear signal transduction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for DIP13B Antibody (NBP2-16165)(3)

Publications using NBP2-16165

• Gaspar RC, Munoz VR, Kuga GK, et al. Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice Eur. J. Neurosci. 2019-06-17 [PMID: 31206806]
• Canciglieri PH, Kuga GK, Munoz VR et al. The reversal effect of physical exercise on aging-related increases in APPL2 content in skeletal muscle. Life Sci. 2018-10-01 [PMID: 30189216] (WB, Rat)
• Gaspar R, Munoz V, Formigari G et al. Acute physical exercise increases the adaptor protein APPL1 in the hypothalamus of obese mice. Cytokine [PMID: 29705396] (Mouse)

Bioinformatics

• Gene Symbol: APPL2
• Uniprot:
  • Q8NEU8(Human)