DHX58 Antibody Pair

Product Discontinued

DHX58 Antibody Pair Summary

• Description: Quality control test: Immunoprecipitation-Western Blot (IP-WB). This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  
  
• Antibody pair for IP: rabbit polyclonal anti-DHX58 (300 ul)
• Antibody pair for WB: mouse purified polyclonal anti-DHX58 (50 ug)
• Clonality: Polyclonal
• Gene: DHX58
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for DHX58 Antibody Pair

• D11lgp2e
• D11LGP2probable ATP-dependent RNA helicase DHX58
• DEXH (Asp-Glu-X-His) box polypeptide 58
• EC 3.6.4.13
• LGP2ortholog of mouse D11lgp2
• Probable ATP-dependent helicase LGP2
• Protein D11Lgp2 homolog
• RIG-I-like receptor LGP2
• RLR
• RNA helicase LGP2

Background

Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interactswith DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, inparticuliar HCV RNA. Binding occurs at blunt dsRNA termini

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: DHX58