DGK-gamma Antibody (613531) [Janelia Fluor® 525]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 613531
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 525

DGK-gamma Antibody (613531) [Janelia Fluor® 525] Summary

• Immunogen: E. coli-derived recombinant human DGK‑ gamma
  Gly2-Ser126
  Accession # P49619
• Specificity: Detects human, mouse, and rat DGK‑ gamma in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DGKG
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DGK-gamma Antibody (613531) [Janelia Fluor® 525]

• DAG kinase gamma
• DAGK3
• DAGK3MGC104993
• DGKG
• DGKgamma
• DGK-gamma
• diacylglycerol kinase gamma
• diacylglycerol kinase, gamma (90kD)
• diacylglycerol kinase, gamma 90kDa
• diacylglyerol kinase gamma
• Diglyceride kinase gamma
• EC 2.7.1.107
• MGC133330

Background

DGKG encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DGKG