Desmoplakin [p Ser2849] Antibody - C-terminus

• Reactivity: Hu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

Desmoplakin [p Ser2849] Antibody - C-terminus Summary

• Immunogen: A synthetic peptide near the C-terminus of human Desmoplakin protein.
• Modification: p Ser2849
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DSP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: This antibody tested in ELISA and western blot and is useful for Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~331kDa corresponding to the appropriate cell lysate or extract.

Reactivity Notes

BLAST analysis was used to suggest cross-reactivity with mouse and human based on 100% sequence homology. Cross-reactivity with Desmoplakin pS2849 from other sources has not been determined.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 30% Glycerol
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for Desmoplakin [p Ser2849] Antibody - C-terminus

• 250/210 kDa paraneoplastic pemphigus antigen
• DCWHKTA
• desmoplakin (DPI, DPII)
• desmoplakin I
• desmoplakin II
• Desmoplakin
• DP
• DPI
• DPII
• DSP
• KPPS2
• PPKS2

Background

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DSP