Desmoplakin Antibody

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Orthogonal Strategies: Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-49158] - Analysis in human skin and lymph node tissues using NBP2-49158 antibody. Corresponding DSP RNA-seq data are presented for ...read more
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-49158] - Staining of human lymph node shows very weak positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-49158] - Staining of human endometrium shows very weak positivity in glandular cells.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-49158] - Staining of human heart muscle show strong membranous and cytoplasmic positivity in intercalated disc in cardiomyocytes.
Immunohistochemistry-Paraffin: Desmoplakin Antibody [NBP2-49158] - Staining of human skin shows moderate cytoplasmic positivity in squamous epithelial cells.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

Desmoplakin Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: RELDECFAQANDQMEILDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPRVRRASSKGGGGYTCQSGSGWDEFTKHVTSECLGW
Predicted Species
Mouse (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DSP
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Desmoplakin Recombinant Protein Antigen (NBP2-49158PEP)

Reactivity Notes

Rat (89%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Desmoplakin Antibody

  • 250/210 kDa paraneoplastic pemphigus antigen
  • DCWHKTA
  • desmoplakin (DPI, DPII)
  • desmoplakin I
  • desmoplakin II
  • Desmoplakin
  • DP
  • DPI
  • DPII
  • DSP
  • KPPS2
  • PPKS2

Background

Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DSP