DEC-205/CD205 Antibody (AP-MAB0873)

Product Discontinued

DEC-205/CD205 Antibody (AP-MAB0873) Summary

• Immunogen: Mouse lymph node stroma
• Specificity: This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with Mouse lymph node stroma.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Gene: LY75
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry 1:10-1:1000
  • Western Blot 1:100-1:2000
• Application Notes: Flow Cytometry and Western Blot. Extremely low level of LPS (< 0.002EU/ug IgG). This antibody is CyTOF ready.

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: A 0.2 um filtered solution in PBS - Azide free
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Protein A or G purified

Alternate Names for DEC-205/CD205 Antibody (AP-MAB0873)

• CD205
• CLEC13B
• C-type lectin domain family 13 member B
• DEC205
• DEC-205
• GP200-MR6
• Ly75
• Ly-75
• Lymphocyte antigen 75

Background

Mouse CD205, also known as DEC-205 (dendritic and epithelial cells, 205 kDa). CD205 is an integral membrane glycoprotein involved in antigen uptake, trafficking and presentation that improves the induction of antigen-specific T cell immunity. CD205 is highly expressed by CD8+ dendritic cells (DCs) and also expressed at different levels by bone marrow Gr1+ cells, Langerhans cells, (BMDC) bone marrow derived DCs and thymic epithelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LY75
• Entrez:
  • 17076(Mouse)