DEC-205/CD205 Antibody (523218) [Alexa Fluor® 532]

• Reactivity: Hu
• Applications: WB
• Clone: 523218
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

DEC-205/CD205 Antibody (523218) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human DEC‑205/CD205
  Cys216-Cys501
  Accession # O60449
• Specificity: Detects human DEC‑205/CD205 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant mouse DEC-205 is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DEC-205/CD205 Antibody (523218) [Alexa Fluor® 532]

• CD205
• CLEC13B
• C-type lectin domain family 13 member B
• DEC205
• DEC-205
• GP200-MR6
• Ly75
• Ly-75
• Lymphocyte antigen 75

Background

DEC-205, also known as CD205 and lymphocyte antigen 75 (Ly 75), is a type I transmembrane protein that is primarily expressed on dendritic cells and thymic epithelial cells. The extracellular region of DEC-205 contains ten C-type lectin-like domains, a fibronectin type II domain and a ricin B-type lectin domain. DEC-205 functions as an endocytic receptor for antigens. The recombinant protein used to generate the anti-human DEC-205 antibody contains the first two C-type lectin domains.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.