DDOST Antibody (02) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: ELISA
• Clone: 02
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

DDOST Antibody (02) [Alexa Fluor™ Plus 594] Summary

• Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DDOST (Uniprot#: P39656-1; Ser43-Pro427).
• Specificity: No cross-reactivity in ELISA with: E.coli cell lysate
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: DDOST
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

No cross-reactivity in ELISA with: E.coli cell lysate

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DDOST Antibody (02) [Alexa Fluor™ Plus 594]

• advanced glycation endproduct receptor 1
• DDOST 48 kDa subunit
• dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
• dolichyl-diphosphooligosaccharide-protein glycosyltransferase
• dolichyl-diphosphooligosaccharide--protein glycosyltransferase
• dolichyl-diphosphooligosaccharide-protein glycotransferase
• EC 2.4.1.119
• KIAA0115MGC2191
• Oligosaccharyl transferase 48 kDa subunit
• oligosaccharyltransferase 48 kDa subunit
• OST48AGER1
• OSTOKSWcl45
• WBP1

Background

DDOST encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DDOST