DC-STAMP/TM7SF4 Antibody (788524) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: Flow, CyTOF-ready
• Clone: 788524
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

DC-STAMP/TM7SF4 Antibody (788524) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Immunogen: E. coli-derived recombinant human DC-STAMP
  Asp314-Thr376
  Accession # Q9H295
• Specificity: Detects human DC-STAMP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse DC-STAMP is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DCSTAMP
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for DC-STAMP/TM7SF4 Antibody (788524) [CoraFluor™ 1]

• DCSTAMP
• DC-STAMP
• dendritic cell-specific transmembrane protein
• FIND
• IL-4-induced Protein
• TM7SF4
• transmembrane 7 superfamily member 4

Background

Dendritic cells are unique in their ability to present antigen to naive T cells, and therefore play a central role inthe initiation of immune responses. The protein encoded by this gene is a transmembrane molecule that ispreferentially expressed by dendritic cells. Its expression is down-regulated by ligation of the CD40 molecule.Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of someof these variants has not been determined. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DCSTAMP