DARC Antibody [Janelia Fluor® 525]

• Reactivity: Mu, Rt
• Applications: WB, Flow, IHC, CyTOF-ready
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Janelia Fluor 525

DARC Antibody [Janelia Fluor® 525] Summary

• Immunogen: E. coli-derived recombinant mouse DARC
  Met1-Pro61, Ala115-Cys127, Ser186-Lys205, Tyr264-Asn285
  Accession # NP_034175
• Specificity: Detects mouse and rat DARC in Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: DARC
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DARC Antibody [Janelia Fluor® 525]

• ACKR1
• CCBP1
• CD234 antigen
• CD234
• DARC
• Dfy
• Duffy Antigen
• Duffy antigen/chemokine receptor
• Duffy blood group antigen
• Duffy blood group, chemokine receptor
• Fy Antigen
• Fy glycoprotein
• FYDuffy blood group
• Glycoprotein D
• GPD
• GPDWBCQ1
• GpFy
• Plasmodium vivax receptor

Background

DARC is a non-specific receptor for many chemokines such as IL-8, GRO, RANTES, MCP-1 and TARC. It is also the receptor for the human malaria parasites Plasmodium vivax and Plasmodium knowlesi.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DARC