Recombinant Human D4-GDI/RhoGDI2 Protein

Product Discontinued

Recombinant Human D4-GDI/RhoGDI2 Protein Summary

• Description: Recombinant protein for Human D4-GDI/RhoGDI2
  
  

  Source:E. coli
  Amino Acid Sequence:(NM_004309)

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: ARHGDIB
• Purity: >90%, by SDS-PAGE
• Endotoxin Note: <0.1 ng/ug

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 54 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Sterile filtered in 50mM Tris-Acetate, pH 7.5, 1mM EDTA, 20% Glycerol.
• Concentration: 0.1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Recombinant Human D4-GDI/RhoGDI2 Protein

• ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
• D4
• GDIA2
• GDID4
• LYGDI
• Ly-GDI
• RAP1GN1
• RhoGDI2

Background

D4-GDI belongs to the family of rho-GDI or GDP-dissociation inhibitors for the Rho/Rac family of small G proteins; consisting of rhoGDI-1, D4-GDI/rhoGDI-2 and rhoGDI-3. It inhibits the release of GDP from the Rho proteins, essential for GTP-loading and activation of GTPase activity. D4-GDI is located in the cytoplasm and is involved in the regulation of the membrane association and dissociation cycle of Rho/Rac proteins. It is known to be a substrate for caspase 3 during Fas-mediated apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ARHGDIB