Cytosolic Sulfotransferase 1A1/SULT1A1 Antibody [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, IP
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 405

Cytosolic Sulfotransferase 1A1/SULT1A1 Antibody [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human Cytosolic Sulfotransferase 1A1/SULT1A1
  Glu2-Leu295
  Accession # P50225
• Specificity: Detects human Cytosolic Sulfotransferase 1A1/SULT1A1 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human SULT1E1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cytosolic Sulfotransferase 1A1/SULT1A1 Antibody [Alexa Fluor® 405]

• Aryl sulfotransferase 1
• Cytosolic Sulfotransferase 1A1
• EC 2.8.2
• EC 2.8.2.1
• HAST1/HAST2
• Phenol sulfotransferase 1
• Phenol-sulfating phenol sulfotransferase 1
• P-PST 1
• P-PST
• PST
• ST1A1
• ST1A3
• STP1
• STP1MGC5163
• STPMGC131921
• sulfotransferase 1A1
• sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
• SULT1A1
• Thermostable phenol sulfotransferase
• thermostable phenol sulfotransferase1
• ts-PST
• TSPST1

Background

Cytosolic sulfotransferases catalyze the sulfonation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are distinct from Golgi resident sulfotransferases by the absence of transmembrane domains and are located in the cytoplasm (1, 2). SULT1A1 is one of two phenol sulfotransferases with thermostable enzyme activity (2). The enzyme is more specific for sulfonation on catecholamines, phenolic drugs and neurotransmitters (3). Because of its ability to modify diverse promutagen and procarcinogen xenobiotics, it is implicated in a range of cancers (2). The crystal structure of the enzyme reveals that its active site is flexible and can accommodate diverse hydrophobic substrates with varying sizes, shapes and flexibility (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.