Cytokeratin 8/18 Antibody (KRT8.18/4997R) [DyLight 650]

• Reactivity: Hu
• Applications: IHC
• Clone: KRT8.18/4997R
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: DyLight 650

Cytokeratin 8/18 Antibody (KRT8.18/4997R) [DyLight 650] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant full-length human CK8 and CK8 proteins
• Localization: Cytoplasm
• Specificity: This monoclonal antibody cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stainedImmunohistochemical staining with this monoclonal antibody is indistinguishable from that obtained with monoclonal antibody 5D3
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: KRT8
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Cytokeratin 8/18 Antibody (KRT8.18/4997R) [DyLight 650]

• CARD2
• CK8
• CK-8
• CYK8cytokeratin 8
• Cytokeratin-8
• K2C8
• K8cytokeratin-8
• keratin 8
• keratin, type II cytoskeletal 8
• keratin-8
• KO
• Type-II keratin Kb8

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: KRT8