Cytokeratin 19 Antibody (E6)

• Reactivity: Rt, Fi, Rb, Hu(-), Mu(-)
• Applications: WB, ICC/IF, IHC
• Clone: E6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Cytokeratin 19 Antibody (E6) Summary

• Description: Novus Biologicals Mouse Cytokeratin 19 Antibody (E6) (NBP2-29804) is a monoclonal antibody validated for use in IHC, WB and ICC/IF. Anti-Cytokeratin 19 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Keratin from rat colon.
• Marker: Epithelial Cell Marker
• Specificity: Rat keratin 19 (40kD), analogous to human keratin 19.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: KRT19
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen
  • Western Blot 1:100-1:2000
• Application Notes: Use in ICC/IF reported in secitific publication PMID: 32391922

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Ascites
• Preservative: No Preservative
• Purity: Unpurified

Alternate Names for Cytokeratin 19 Antibody (E6)

• 40-kDa keratin intermediate filament
• CK19
• CK-19
• Cytokeratin 19
• EndoC
• K19
• K1CS
• keratin 19
• keratin, type I cytoskeletal 19
• keratin, type I, 40-kd
• keratin-19
• Krt19
• MGC15366

Background

Cytokeratin 19 (also known as Keratin, type I cytoskeletal 19) belongs to the keratin family which consists of fibrous proteins that make up the framework of epithelial cells. Cytokeratin 19 plays a role in the organization of myofibers. This protein is known to have interactions with ZNF638, FANCG, FAM107A, KRT15 and EXOC8. Cytokeratin 19 has been studied in relation to several disorders and diseases including chordoma, adenoma, hamartoma, adenoiditis, carcinoma, and liver disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cytokeratin 19 Antibody (NBP2-29804)(3)

Publications using NBP2-29804

• Wang L, Yang X, Wan L et al. ARHGAP17 inhibits pathological cyclic strain-induced apoptosis in human Periodontal Ligament Fibroblasts via Rac1/Cdc42 Clin. Exp. Pharmacol. Physiol. 2020-05-11 [PMID: 32391922] (ICC/IF, Human)
• Murakami S, Soyama A, Miyamoto D et al. Transplantation of chemically-induced liver progenitor cells ameliorates hepatic fibrosis in mice with diet-induced nonalcoholic steatohepatitis Regenerative Therapy 2022-12-01 [PMID: 36475025] (ICC/IF, IF/IHC, Rat)

Bioinformatics

• Gene Symbol: KRT19
• Uniprot:
  • P08727()
  • Q63279(Rat)