Cytokeratin 10 Antibody (DE-K10) [Alexa Fluor® 488]

• Reactivity: Hu, Ca, Fe
• Applications: IHC
• Clone: DE-K10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Cytokeratin 10 Antibody (DE-K10) [Alexa Fluor® 488] Summary

• Immunogen: Cytoskeletal preparation extracted from human ectocervical epithelium (Uniprot: P13645)
• Localization: Cytoplasmic
• Marker: Suprabasal Epithelial Marker
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: KRT10
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Cytokeratin 10 Antibody (DE-K10) [Alexa Fluor® 488]

• BCIE
• BIE
• CK10
• CK-10
• cytokeratin 10
• Cytokeratin-10
• EHK
• K10keratosis palmaris et plantaris
• Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris)
• keratin 10
• keratin, type I cytoskeletal 10
• keratin-10
• KPP

Background

This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cytokeratin 10 Antibody (NBP2-54402AF488)(2)

Publications using NBP2-54402AF488

• Radtke Aj, Chu Cj, Yaniv Z Et Al. IBEX: An open and extensible method for high content multiplex imaging of diverse tissues arXiv preprint 2021-01-01
• Radtke AJ, Chu CJ, Yaniv Z Et al. IBEX: an iterative immunolabeling and chemical bleaching method for high-content imaging of diverse tissues Nat Protoc 2022-01-13 [PMID: 35022622] (Hydrolysis Assay, Human)
  
  Details:
  Citation using the Alexa Fluor 532 version of this antibody.

Bioinformatics

• Gene Symbol: KRT10