Cytochrome P450 2C18 Antibody - Azide and BSA Free

Western Blot: Cytochrome P450 2C18 Antibody [H00001562-B01P] - Analysis of CYP2C18 expression in transfected 293T cell line by CYP2C18 polyclonal antibody. Lane1:CYP2C18 transfected lysate(53.9 KDa). Lane2:Non-transfected lysate.

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Cytochrome P450 2C18 Antibody - Azide and BSA Free Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: CYP2C18 (NP_000763.1, 1 a.a. - 490 a.a.) full-length human protein. MDPAVALVLCLSCLFLLSLWRQSSGRGRLPSGPTPLPIIGNILQLDVKDMSKSLTNFSKVYGPVFTVYFGLKPIVVLHGYEAVKEALIDHGEEFSGRGSFPVAEKVNKGLGILFSNGKRWKEIRRFCLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSVIFHDRFDYKDQRFLNLMEKFNENLRILSSPWIQVCNNFPALIDYLPGSHNKIAENFAYIKSYVLERIKEHQESLDMNSARDFIDCFLIKMEQEKHNQQSEFTVESLIATVTDMFGAGTETTSTTLRYGLLLLLKYPEVTAKVQEEIECVVGRNRSPCMQDRSHMPYTDAVVHEIQRYIDLLPTNLPHAVTCDVKFKNYLIPKGTTIITSLTSVLHNDKEFPNPEMFDPGHFLDKSGNFKKSDYFMPFSAGKRMCMGEGLARMELFLFLTTILQNFNLKSQVDPKDIDITPIANAFGRVPPLYQLCFIPV
• Specificity: CYP2C18 - cytochrome P450, family 2, subfamily C, polypeptide 18,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: CYP2C18
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytochrome P450 2C18 Antibody - Azide and BSA Free

• (S)-mephenytoin hydroxylase associated cytochrome P450
• CPCI
• CYP2C
• CYP2C17
• CYPIIC18
• cytochrome P450 2C18
• cytochrome P450, family 2, subfamily C, polypeptide 18
• cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17
• cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18
• Cytochrome P450-6b/29c
• DKFZp686I24235
• EC 1.14.14.1
• flavoprotein-linked monooxygenase
• microsomal monooxygenase
• P450-6B/29C
• P450IIC17
• unspecific monooxygenase

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CYP2C18
• Entrez:
  • 1562(Human)
• Uniprot:
  • NP_000763.1(Human)