Cytochrome P450 2C18 Products

Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez	1562 Human
Uniprot	NP_000763.1 Human
Product By Gene ID	1562
Alternate Names	(S)-mephenytoin hydroxylase associated cytochrome P450 CPCI CYP2C CYP2C17 CYPIIC18 cytochrome P450 2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17 cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18 Cytochrome P450-6b/29c DKFZp686I24235 EC 1.14.14.1 flavoprotein-linked monooxygenase microsomal monooxygenase P450-6B/29C P450IIC17 unspecific monooxygenase

Research Areas for Cytochrome P450 2C18

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Lipid and Metabolism