Cytochrome P450 1A2 Antibody

Images

 
Western Blot: Cytochrome P450 1A2 Antibody [NBP1-97780] - staining of Human Liver (A) and (1ug/ml) Lung (B) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Western Blot: Cytochrome P450 1A2 Antibody [NBP1-97780] - (1ug/ml) Analysis of fetal Mouse Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Cytochrome P450 1A2 Antibody Summary

Immunogen
Peptide with sequence C-HSENYKDNGGLIPEEK corresponding to internal region according to Uniprot Mouse NP_034123.1.
Specificity
This antibody is not expected to cross-react to the similar P450 1A1.
Predicted Species
Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CYP1A2
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1 - 3 ug/ml
  • Peptide ELISA Detection limit 1:32000
Application Notes
WB: Approx. 60 kDa band observed in mouse fetal liver lysates (calculated MW of 58.2 kDa band according to NP_034123.1).
Publications
Read Publication using NBP1-97780.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cytochrome P450 1A2 Antibody

  • aryl hydrocarbon hydroxylase
  • CP12
  • CYPIA2
  • Cytochrome P(3)450
  • cytochrome P450 1A2
  • Cytochrome P450 4
  • cytochrome P450, family 1, subfamily A, polypeptide 2
  • cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2
  • Cytochrome P450-P3
  • dioxin-inducible P3-450
  • EC 1.14.14.1
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • P3-450
  • P450 form 4
  • P450(PA)
  • xenobiotic monooxygenase

Background

In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cytochrome P450 1A2 Antibody (NBP1-97780)(1)

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Bioinformatics

Gene Symbol CYP1A2
Entrez
Uniprot