Cytochrome P450 1A1/1A2 Products

Description

P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. NADPH cytochrome P450 reductase is a microsomal enzyme responsible for the transfer of electrons from NADPH to cytochrome P450 enzymes during the P450 catalytic cycle. NADPH cytochrome P450 reductase is localized to the endoplasmic reticulum where it is also able to transfer electrons to heme oxygenase and cytochrome beta5. NADPH cytochrome P450 reductase is structurally related to two separate flavoprotein families, ferredoxin nucleotide reductase (FNR) and flavodoxin. Electron transfer of NADPH cytochrome P450 reductase requires the binding of two flavin cofactors, FAD and FMN, to the FNR and flavodoxin domains, respectively.

Bioinformatics

Product By Gene ID	1543
Alternate Names	AHH AHRR aryl hydrocarbon hydroxylase CP11 CYP1 CYPIA1 cytochrome P1-450, dioxin-inducible cytochrome P450 1A1 Cytochrome P450 form 6 cytochrome P450, family 1, subfamily A, polypeptide 1 Cytochrome P450-C Cytochrome P450-P1 EC 1.14.14.1 flavoprotein-linked monooxygenase P1-450 P450-C P450DX subfamily I (aromatic compound-inducible), polypeptide 1 xenobiotic monooxygenase

Research Areas for Cytochrome P450 1A1/1A2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Lipid and Metabolism