Cysteine Dioxygenase Type 1 Recombinant Protein Antigen

Product Discontinued

Cysteine Dioxygenase Type 1 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human CDO1.
  
  

  Source: E. coli

  Amino Acid Sequence: LKETLFAWPDKKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMTFHSKFGIRTPNATSGSL

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: CDO1
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-33988.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 29 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for Cysteine Dioxygenase Type 1 Recombinant Protein Antigen

• CDO
• CDO-I
• cysteine dioxygenase type 1
• Cysteine dioxygenase type I
• cysteine dioxygenase, type I
• EC 1.13.11.20

Background

Cysteine Dioxygenase Type 1 is a 23 kDa 200 amino acid protein which has a role in initiating metabolic pathways as well as altering intracellular cysteine and glutathione levels. Cysteine Dioxygenase Type 1 is known to interact with VHL, MAPK14, SPAG9, CSAD and CTH. Cysteine Dioxygenase Type 1 has been studied in relation to breast cancer, cutaneous t cell lymphoma, hepatoblastoma and hepatitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: CDO1