Cyclin-O Antibody

Immunohistochemistry-Paraffin: Cyclin-O Antibody [NBP2-14806] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: Cyclin-O Antibody [NBP2-14806] - Staining of human stomach shows moderate cytoplasmic positivity in subset glandular cells.

Immunohistochemistry-Paraffin: Cyclin-O Antibody [NBP2-14806] - Staining of human pancreas shows moderate cytoplasmic positivity in islets of Langerhans.

Immunohistochemistry-Paraffin: Cyclin-O Antibody [NBP2-14806] - Staining of human skeletal muscle shows no cytoplasmic positivity in myocytes as expected.

Product Discontinued

Cyclin-O Antibody Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to the amino acids: GRRDNDQNLRAPVKKSRRPRLRRKQPLHPLNPCPLPGDSGICDLFESPSSGSDGAESPSAARGGSPLPGPAQPVAQLDLQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCNO
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24747639)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Cyclin-O Antibody

• CCNO cyclin O
• CCNU
• UDG2

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Cyclin-O Antibody (NBP2-14806)(1)

Publication using NBP2-14806

• Wallmeier J, Al-Mutairi DA, Chen CT et al. Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia. Nat Genet 2014-06-01 [PMID: 24747639]

Bioinformatics

• Gene Symbol: CCNO