Cyclin L2 Antibody

Images

 
Western Blot: Cyclin L2 Antibody [NB100-87009] - Detection of Human Cyclin L2 on HeLa whole cell lysate using NB100-87009. Cyclin L2 was also immunoprecipitated by rabbit anti-Cyclin L2 antibody NB100-87008.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

       

Order Details

Cyclin L2 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 470 and 520 of human cyclin L2 using the numbering given in entry NP_112199.2 (GeneID 81669).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCNL2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Publications
Read Publication using
NB100-87009 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Cyclin L2 Antibody

  • ania-6b
  • CCNM
  • cyclin L2
  • cyclin M
  • cyclin-L2
  • DKFZp761A1210
  • DKFZp762O195
  • HCLA-ISO
  • HLA-ISO
  • Paneth cell-enhanced expression protein
  • PCEE
  • SB138

Background

Cyclin L2 is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression and transcription. The hallmark characteristic of cyclins is the periodicity of their expression and activity that is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin L2 is part of a group of cyclins that are involved in transcriptional regulation at the level of RNA transcription, initiation, elongation, and RNA processing. The transcriptional regulating cyclins include cyclin C, H, K, L1, L2, T1, and T2 which associate with CDK7, -8, -9, -10 and -12. Cyclin L2 associates with CDK11 and RNA polymerase II and co-localizes with splicing factors and is implicated to play a role in pre-mRNA splicing. Alternate names for cyclin L2 include cyclin M, paneth cell-enhanced expression protein, CCNM, and CCNL2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Cyclin L2 Antibody (NB100-87009)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Secondary Antibodies

 

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Cyclin L2 NB100-87009

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Bioinformatics

Gene Symbol CCNL2
Entrez
Uniprot