Cyclin C Antibody

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Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB, IP, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Cyclin C Antibody Summary

Immunogen
A synthetic peptide corresponding to aa 290-303 (Cys-QGPNGSQNSSYSQS) from the C-terminal of human cyclin C
Localization
Nuclear
Specificity
Cyclin C
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCNC
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 5 - 10 ug/mL
  • Immunoprecipitation 10 ug/mg
  • Immunofluorescence 1:10 - 1:500
Positive Control
HeLa Lysate (NB800-PC1)
Cyclin C Lysate (NBL1-08869)

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
1 mg/ml
Purity
Protein A purified

Alternate Names for Cyclin C Antibody

  • CycC
  • cyclin C
  • cyclin-C
  • hSRB11
  • SRB11 homolog

Background

Cyclin C was originally identified by a genetic screen for human and Drosophila cDNAs that complement a triple knock-out of the CLN genes in Saccharomyces cerevisiae. Cyclin C is a nuclear protein present in a multiprotein complex. It interacts both in vitro and in vivo with cdk8, a novel protein-kinase of the cdk family. It is suggested that cyclin C and cdk8 control RNA polymerase II function. Human cdk8-cyclin C might be functionally associated with the mammalian transcription apparatus, perhaps involved in relaying growth-regulatory signals.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CCNC
Entrez
Uniprot